An In-depth Look into Hemochromatosis

Last Updated on Mon, 8 January 2024 | Medical Conditions And Diseases

Hemochromatosis, which affects around 1 in 200 people of Northern European descent, is relatively common. The body is not able to control iron absorption. This leads to a buildup of excessive iron in organs and tissue. Untreated hemochromatosis may lead to serious health problems such as liver and heart disease. Many people are unaware that this disease can be severe until a family member or themselves is diagnosed.

Hemochromatosis: What is it?

Hemochromatosis, or iron overload disorder is when the body absorbs excessive amounts of iron through food. It is believed that the excess iron can be stored in organs such as your heart, liver and pancreas. This could lead to serious conditions like cirrhosis and heart disease. The Centers for Disease Control and Prevention estimate that approximately one million Americans are affected by hemochromatosis.

Hemochromatosis: Common Causes

Hemochromatosis is primarily caused by a mutation of the HFE gene. The most common forms are C282Y or H63D. The mutations cause:

The most common form of hereditary hemochromatosis is caused by mutations to the HFE gene.
The HJV gene or the HAMP gene can cause juvenile hemochromatosis.
The cause of neonatal hemochromatosis is unknown, but the disease may be caused by an autoimmune disorder.

The disorder is often caused by other conditions, such as chronic anemia and alcoholism.

Hemochromatosis Treatments: Common Treatments

There is no cure for the disease, but treatments aim to reduce iron levels in the body. This can help prevent symptoms or ease them. Common treatments include:

Regular removal of blood is necessary to reduce iron levels. The most common method of treatment is phlebotomy.
When phlebotomy cannot be used, chelation therapy is usually prescribed.
Iron levels can be controlled by adjusting your diet. Avoiding iron-rich food, taking vitamin C and alcohol, or avoiding foods rich in iron.

The treatments have been effective at managing symptoms and preventing the complications that are associated with hemochromatosis.

Hemochromatosis: Expert opinions

Early detection and treatment of hemochromatosis is crucial for preventing serious health problems. Leading researcher Dr. James Barton emphasizes that genetic testing is important for families who have a family history of hemochromatosis. The American Liver Foundation also recommends regular blood tests to detect iron overload early.

The best natural remedies, prevention measures, and tips

Although medical treatment is required to manage hemochromatosis certain lifestyle changes can help support the treatment. They include:

A balanced diet that is low in iron.
To prevent liver damage, avoid alcohol.
Avoid vitamin C as it can increase iron absorption.

These methods are meant to complement and not substitute medical treatment.

Hemochromatosis, in a nutshell is a severe but treatable disease. The condition is caused by genetic mutations which lead to an iron overload. Early detection and treatment are the best ways to control and avoid complications. Lifestyle changes, such as diet modifications, can help manage the disease. It is important to raise awareness of this disease as our knowledge about hemochromatosis evolves. This will help to encourage early diagnosis and treatment.